Chapter 4 - Central nervous system

Formulary List for Walsall Healthcare NHS Trust (asper categories of the BNF)

BNF Chapter 4 Central Nervous System Formulary-Status Key
   Indicates that the drug is available as part of a shared care agreement
  Indicates that the drug is available, by prior approval, to patients that meet NICE criteria 
   Indicates that the drug is only available from hospital(s)
traffic light pic Medicines with positive NICE TAs added to the formulary but awaiting local clarification on their place in therapy

 Drug name

 Drugs shown in black are first line choices

 

 Drugs shown in orange are second line choices

  Drugs shown in red are not recommended

Chapter 4

Central nervous system

Hospital Formulary

Status

Joint Walsall Formulary

Type of drug

Name of drug

 

   

 

Hypnotics & Anxiolytics

 

Melatonin

Melatonin Pathway default

DWMH guidance on melatonin in children

 

Zopiclone

Zolpidem

Chloral Hydrate (Paed Specialist only)

Diazepam

Chlordiazepoxide (Alcohol withdrawal only)

Lorazepam

 

default Benzo ( 2013-03-27 10:45:39) (773 KB)

default Anxiolytics and Hypnotics ( 2013-07-09 09:25:14) (133 KB)

TA77 Insomnia

NICE CG53

NICE CG137

TA77 Insomnia

NICE CG115

Oxazepam

Nitazepam

Flurazepam

Loprazolam

Lormetazepam

Temazepam

Clomethiazole

Buspirone

   

PSYCHOSES & RELATED DISORDERS

       

Antipsychotics

Haloperidol (short term only)

Levomepromazine (Palliative Care use only)

 

default Schizophrenia ( 2013-03-27 10:31:56) (543 KB)

NICE CG82

Atypical Antipsychotics

Initiation of atypical antipsychotics agents must follow Specialist Mental Health Team advices.

Olanzapine

Risperidone

Quetiapine- Biquelle TM 

or Mintreleq XL or ZaluronTM                                                

 

NICE CG42

NICE CG82

NICE CG38

ANTIDEPRESSANTS

      document Depression V2 (475 KB)

NICE CG90

NICE CG28

NICE CG91

Tricyclic antidepressants

Initiation of tricyclic antidepressant for treatment of depression must follow Specialist Mental Health Team advices.

Amitriptyline

Clomipramine

Dosulepin

Imipramine

Lofepramine

Nortriptyline

Trimipramine

Trazodone

 

NICE CG45

NICE CG31

NICE CG111

SSRI

Citalopram

Fluoxetine

Sertraline

Paroxetine

   

 

NICE CG38

 NICE CG90

NICE CG113

Mirtazapine

Escitalopram

 

CNS Stimulants

Methylphenidate [Xaggitin XL preferred brand for modified release]

Atomoxetine

Lisdexamphetamine

 

 

NICE TA 98

NICE CG72

Modafinil-Heurologist only

 

   
Selective alpha2 - adrenergic receptor agonist Guanfacine    
Serotonin modulator and stimulator (SMS) Vortioxetine - 3rd line choice in line with NICE TA     NICE TA367

Anti-obesity

Orlistat

Naltrexone with Bupropion

 

 

                      Not recommended as per NICE TA 494

 

NICE CG43

NICE TA494

Drugs used in Nausea & Vertigo

 

Metoclopramide

Prochlorperazine

Cyclizine

Domperidone

Hyoscine hydromide

Ondansetron

Betahistine

Cinnarizine

 

   

Granisetron patch

   

 Nabilone

ANALGESICS

  document Opioids in Pregnancy (79 KB)

document Opioids in Renal Impairment (78 KB)

document Opioid Conversions excluding Fentanyl (47 KB)

document Morphine to Fentanyl Conversion (54 KB)

 

document (167 KB) document Chronic Pain Pathway Secondary Care 2014 (2 MB)

 

Non-opioid analgesics

 

Aspirin

Paracetamol

Co-codamol 8/500

Co-codamol 30/500

Co-dydramol 10/500

 

 

NICE CG88

Nefopam

   

Opioid analgesics

DCD = Controlled drug prescription requirements apply

 

Buprenorphine DCD [Butec/Sevodyne]

Codeine injection DCD

Codeine tablet/syrup

Diamorphine DCD

Fentanyl DCD [Fencino/Mezolar/Matrifen]

Hydromorphine DCD

Meptazinol                                               

Methadone DCD

Morphine Sulphate DCD

Oxycodone DCD modified release [Lynlor/ Reltebon/Longtec/Abtard]

Oxycodone DCD immediate release [Shortec]

Pethidine DCD                    NICECG55

Tramadol

Dihydrocodeine

 

default

default Palliative ( 2013-03-27 10:32:09) (805 KB)

NICE CG140

Pentazocin

Papavertum

Tapentadol- Hospital Only Initiation (Blueteq form must be completed for monitoring/compliance)

   

Neuropathic Pain

Amitriptyline                                     

Gabapentin

Pregabalin

Duloxetine

 

 

NICE CG173

 

Antimigraine drugs

Sumatriptan

Pizotifen (prophylaxis)

     

Rizatriptan

Zolmitriptan

 

 

NICECG150

ANTIEPILEPTICS

       

Oral antiepileptics

Carbamazepine

Carbamazepine MR (Tegretol Retard)

Lamotrigine

Sodium valproate (Epilim Chrono)

Topiramate

Levetiracetam

Phenytoin

Phenobarbital DCD

Clobazam

Clonazepam

Ethosuximide

Gabapentin

Oxcarbazepine

Acetazolamide

Primidone

Tiagabine

Vigabatrin

Lacosamide

Retigabine

Zonisamide

Rufinamide

 

NICECG137

TA 232

Status epilepticus

Clonazepam

Diazepam

Phenytoin

Lorazepam

Midazolam DCD

Phenobarbital DCD

Paraldehyde (Paed only)

 

 

NICECG137

PARKINSON’S DISEASE

     

NICE CG35

Levodopa plus peripheral decarboxylase inhibitor preparations

Co-beneldopa

Co-beneldopa MR

Co-careldopa

Co-careldopa MR

 

pdf Parkinson's (126 KB) default
(126 KB)
 

Non-ergoline Dopamine Agonists

Pramipexole

Pramipexole MR

Ropinirole

Ropinirole MR

Rotigotine

Apomorphine

 

 

NICE CG35

Monoamine-oxidase-B inhibitors

Selegiline

Rasagiline

Safinamide

 

 

NICE CG35

Catechol-O-methyltransferase inhibitors

Entacapone

 

 

NICE CG35

Levodopa plus peripheral decarboxylase inhibitor with entacapone

Stalevo

Sastravi

 

 

NICE CG35

Other antiparkinsonian drugs

Amantadine

 

 

NICE CG35

Antimuscarinic drugs

No longer use routinely in treatment of Parkinson’s Disease because less effective that dopaminergic drugs and associated with cognitive impairment.

Procyclidine

Orphenadrine

Trihexyphenidyl

 

NICECG145

Essential Tremor, chorea, tics.  

Haloperidol

Tetrabenazine

Botulinum A toxin (CCG funding approval only )

Botulinum B toxin (CCG funding approval only )

Riluzole

 

 

 

 

 

traffic light pic

 

NICE CG8

NICE CG8

Nicotine dependence

Potential client should be referred to Walsall Stop Smoking Services

Nicotine Replacement Therapy

Varenicline (GP prescribing only)

Bupropion (GP prescribing only)

 

default Pharmacotherapy ( 2013-03-27 10:32:09) (670 KB)

NICE TA123

NICE PH10

Alcohol dependence

Acamprosate

Disulfiram

Nalmefene

 

 

 

 

NICE CG115

NICE TA 325

Opioid dependence

Potential client should be referred to Lanterns House. Prescriber must not attempt to discharge patient with either drugs.

Methadone

Buprenorphine

 

NICE CG52

NICE TA114

Drugs for Dementia

Donepezil

Galantamine [Gatalin]

Memantine

Rivastigmine

 

NICE CG 42

NICE Pathway